Novel DNA vaccine prevents AD in mouse model

In the current study, the investigator used a triple-transgenic mouse model that grows plaques and tangles in the brain similar to human AD. Four cohorts of between 15 and 24 mice each were injected in the skin with DNA coding for the Abeta42 peptide. The researchers had already shown that full-length DNA Abeta42 trimer immunization was non-inflammatory and…

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Subpopulation of fibroblasts drives breast tumor development

Cancer-associated fibroblasts are especially prominent in breast tumors, but the nature of their function and origin not been uncertain completely. Consequently, recruitment of BM-derived CAFs to primary tumors and metastases resulted in a gradual reduction in PDGFR alpha levels, which was apparently also in human breast tumors, and correlated with worse outcome. The finding that…

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Mechanism explains why damaged DNA amass in ALS neurons

A mechanism that leads to the accumulation of damaged DNA in neurons that characterize amyotrophic lateral sclerosis (ALS). A team of neurodegenerative disease researchers recognizes. ALS is a neurodegenerative disease signalized by the selective and progressive death of upper and lower motor neurons. This leads to ongoing muscle weakness, and death of the patient usually…

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Biotech in Pakistan reached an all-time high in 2017

According to the International Service for the Acquisition of Agri-biotech Applications (ISAAA), Pakistan has achieved a 96 percent adoption rate of Bt cotton, or 3 million hectares of the national total area planted to cotton which was 3.11 million hectares. Around 725,000 smallholder cotton farmers in Pakistan planted and benefitted from Bt cotton in 2017. It…

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Sino-Pak conference on cotton from 26th

‘Innovation in Cotton and Biotechnology’ a two-day Sino-Pak international conference will start on November 26 at Muhammad Nawaz Sharif University of Agriculture (MNSUA). Institute of Plant Breeding and Biotechnology in collaboration with Biotechnology Research Institute China, Bahauddin Zakariya University and Punjab government would organize the conference. MNSUA would welcome scientists from China, USA, Iran, Uzbekistan,…

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Sino-Pak hybrid rice research center opened in China

University of Karachi’s (KU) International Center for Chemical and Biological Sciences (ICCBS) in joint effort with the China National Rice Research Institute (CNRRI) recently inaugurated SINO-Pak Hybrid Rice Research Center (SPHRRC) in China. Senior professor of (ICCBS), Prof. Dr. Atta-ur-Rahman, former chairman higher education commission and federal minister for science and technology, and Dr. Peisong…

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New variety of hybrid wheat seeds successfully developed

Agriculture scientists of the Muhammad Nawaz Sharif University of Agriculture (MNSUA) in alliance with Australian and the United Kingdom scientists managed to develop hybrid wheat seeds successfully and these seeds would be put on display in March-2019. Director Office of Research, Innovation, and Commercialization (ORIC)-MNSUA, Dr. Zulfiqar told to APP. The joint venture programme was…

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Rice, sugarcane production expand in current season:Federal Committee on Agriculture

Cultivation and production targets of sugarcane and rice were achieved, whereas the production of these crops had surpassed set targets for the season 2018-19. Stated   Federal Committee on Agriculture (FCA)The committee met with Federal Secretary Ministry of National Food Security and Research Dr. Muhammad Hashim Popalzai in the chair and reviewed the output of Kharif…

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